Pioneering Progress in CRISPR-Based Genome Editing
Introduction: Advancements in CRISPR Editing
The recent advancements in CRISPR-Cas9 and Genetic Engineering Breakthroughs have been a definitive moment in genome editing. The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas9 system is a technology that has revolutionized the field of genome engineering.
The invention of CRISPR-Cas9 system is a perfect demonstration of how bacterial defense mechanisms can transform human scientific research. In the CRISPR-Cas9 mechanism, the Cas9 protein, guided by a custom guide RNA (gRNA), can bind to specific DNA sequences and cleaves the target DNA at the desired location. The method relies on the cell’s DNA repair apparatus to add, delete, or alter particular DNA sequences.
